Natural Fragrance oils are made in a laboratory but rather than being made from synthetic materials they are created by isolating a single aromatic component from the complex scent of an essential oil. These single components are called isolates. In the chemical profiles created by Mother Nature, the isolates interact with each other and other plant parts to create a wholesome natural essential oil with aromatherapeutic properties. That is not the case with single isolates blended together in a lab.